Fatal Crash Data

US 45 in Mississippi: fatal crashes

From 2015 to 2024, 140 fatal crashes on US 45 in Mississippi killed 159 people, the 5th most of 226 numbered roads in Mississippi. In 2024 there were 17 fatal crashes and 20 deaths on the road.

A US route running through 11 counties of Mississippi. All fatal crashes in Mississippi.

Deaths on US 45 in Mississippi by year

1020201620182020202220242021: 222024: 20
YearFatal crashesDeaths
20241720
202377
20221516
20212222
20201720
201979
20181821
20171116
20161820
201588

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Where on US 45 in Mississippi: the counties with the most fatal crashes

Lee County had the most fatal crashes on US 45 from 2015 to 2024: 24, with 27 deaths. Lee, Monroe and Lowndes counties together held 42% of fatal crashes on US 45 in Mississippi from 2015 to 2024; the 9 listed held 96%. Counties are listed from 5 fatal crashes.

One fatal crash, 2015 to 2024Darker where crashes clusterNot on the map: 1 crash has no location in the file.
County20242015 to 2024Deaths
1Lee County52427
2Monroe County11821
3Lowndes County21720
4Wayne County21619
5Noxubee County21516
6Prentiss County21414
7Clarke County11013
8Lauderdale County01011
9Alcorn County21010

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

When fatal crashes happen on US 45 in Mississippi

140 fatal crashes on US 45 in Mississippi from 2015 to 2024 have a known time, too few for any one weekday and time of day to stand out. The worst hour is 1 pm to 2 pm; the worst month is August.

Share of fatal crashes on US 45 in Mississippi by weekday and time of day, 2015 to 2024, in percent
Midnight to 44 to 8 am8 to noonNoon to 44 to 8 pm8 to midnight
Sun3.6 percent, 5 fatal crashes1.4 percent, 2 fatal crashes2.9 percent, 4 fatal crashes1.4 percent, 2 fatal crashes1.4 percent, 2 fatal crashes2.9 percent, 4 fatal crashes
Mon1.4 percent, 2 fatal crashes1.4 percent, 2 fatal crashes3.6 percent, 5 fatal crashes0.7 percent, 1 fatal crash4.3 percent, 6 fatal crashes0.7 percent, 1 fatal crash
Tue1.4 percent, 2 fatal crashes4.3 percent, 6 fatal crashes2.9 percent, 4 fatal crashes3.6 percent, 5 fatal crashes1.4 percent, 2 fatal crashes2.9 percent, 4 fatal crashes
Wed0.0 percent, 0 fatal crashes2.1 percent, 3 fatal crashes2.1 percent, 3 fatal crashes5.0 percent, 7 fatal crashes2.9 percent, 4 fatal crashes2.9 percent, 4 fatal crashes
Thu0.0 percent, 0 fatal crashes2.1 percent, 3 fatal crashes2.1 percent, 3 fatal crashes3.6 percent, 5 fatal crashes4.3 percent, 6 fatal crashes0.0 percent, 0 fatal crashes
Fri0.0 percent, 0 fatal crashes2.9 percent, 4 fatal crashes3.6 percent, 5 fatal crashes3.6 percent, 5 fatal crashes1.4 percent, 2 fatal crashes3.6 percent, 5 fatal crashes
Sat3.6 percent, 5 fatal crashes1.4 percent, 2 fatal crashes1.4 percent, 2 fatal crashes1.4 percent, 2 fatal crashes2.1 percent, 3 fatal crashes5.7 percent, 8 fatal crashes

By hour

By month

  • Jan7.9%
  • Feb5.7%
  • Mar7.1%
  • Apr4.3%
  • May10.7%
  • Jun8.6%
  • Jul7.9%
  • Aug12.1%
  • Sep5.7%
  • Oct9.3%
  • Nov8.6%
  • Dec12.1%

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

What fatal crashes on US 45 in Mississippi first hit

The first harmful event was a collision with another vehicle in most fatal crashes, 58%; a fixed object such as a tree, pole or barrier in 19%, a pedestrian in 12%, a rollover in 7.1%.

First harmful eventFatal crashesShare
Collision with another vehicle8158%
Fixed object (tree, pole, barrier, ditch)2619%
Pedestrian1712%
Rollover107.1%
Other32.1%
Parked vehicle21.4%
Cyclist10.7%
Not reported00.0%

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

How fatal crashes on US 45 in Mississippi compare with the state

The largest difference from Mississippi: from 2015 to 2024, 34% of fatal crashes on US 45 in Mississippi were at or near an intersection, against 15% across Mississippi. Also above the Mississippi share: rural roads. Below it: drinking drivers and speeding. Shares of fatal crashes from 2015 to 2024, against the share across all of Mississippi. A share is only given over 20 crashes; above or below means more than chance would give on 140 crashes.

US 45Mississippi
On rural stretches87%70%above the Mississippi share
At or near an intersection34%15%above the Mississippi share
In the dark, road unlit37%35%about the same as the Mississippi share
A drinking driver11%19%below the Mississippi share
Speeding3.6%15%below the Mississippi share
A distracted driver (as recorded)2.1%1.7%about the same as the Mississippi share
Occupants killed unbelted47%53%about the same as the Mississippi share
Hit-and-run4.3%3.6%about the same as the Mississippi share
A motorcycle involved5.7%7.3%about the same as the Mississippi share
Pedestrians among the dead12%12%about the same as the Mississippi share

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Questions about fatal crashes on US 45 in Mississippi

How many fatal crashes have there been on US 45 in Mississippi?
140 fatal crashes killed 159 people on US 45 in Mississippi from 2015 to 2024. In 2024 there were 17 fatal crashes and 20 deaths. Source: NHTSA's Fatality Analysis Reporting System (FARS).
Where on US 45 in Mississippi do the most fatal crashes happen?
Lee County had the most fatal crashes on US 45 from 2015 to 2024: 24, with 27 deaths. Monroe County was second with 18.

Other roads in Mississippi with a page

All fatal crashes in Mississippi, with every road ranked.

Where the US 45 numbers come from

Counted from NHTSA's Fatality Analysis Reporting System, 2024 Annual Report File: every fatal crash whose road NHTSA filed as US 45 in Mississippi (filed under 4 spellings, such as "US-45", "US-45 ALTERNATE", "US-45 NORTH", "US-45-278 NOAH CURTIS"). Ramps, frontage and service roads are left out. Where two routes share a road, NHTSA files each crash under one of them, so a shared stretch counts on one route only. A fatal crash is one in which someone died within 30 days. Totals in state and news reports for a road usually differ: they include ramps and frontage roads, or count from preliminary reports. The full method.